LABOKLIN (UK)|Genetic Diseases | Dogs

High dose therapy with the steroid prednisone is the most common treatment for idiopathic encephalitis. Signs include recurring fever, hyperesthesia, cervical rigidity, and anorexia. Puppies with steroid responsive meningitis usually have a fever, they have a stiff or uncoordinated gait, they often resist having their head and neck touched or manipulated and may show signs of severe pain. In addition, this viewpoint that the disease time course correlates with the focal and disseminated forms has more recently been challenged by Demierre et al. I first treated her with a homeopathic vaccine detox agent and a natural supplement that helped her body rid itself of the heavy metals, including mercury and aluminum that are often included in vaccine formulations. Successful EAE induction was based on the following criteria: 1) clear appearance of neurological signs after immunization, 2) positive lesions identified during brain magnetic resonance imaging (MRI) after immunization, and 3) nucleated cell pleocytosis identified by CSF analysis after immunization.

The side effects of the treatment (excessive eating, drinking and urinating including numerous “accidents”) can be overwhelming to the average pet owner. — Boswelia (Frankincense resin) — Fish Oil (a high quality fish oil) — Some of the supplements which I utilized for other purposes also can help with inflammation ( e.g. How often this is required will be dependent on your pet’s response to treatment. Blood and urine samples can identify the underlying infection. Greer KA, AK Wong, H Liu, TR Famula, NC Pedersen, A Ruhe, M Wallace and MW Neff. In the latter case, leukoencephalomalacia was interpreted as a secondary change as a sequel of cardiovascular disturbances caused by the massive alterations in the heart.


These bacteria are Haemophilus influenzae type b, Neisseria meningitidis (causing meningococcal meningitis), and Streptococcus pneumoniae (causing pneumococcal meningitis). Response to therapy is variable and discontinuation results in recurrence of clinical signs and progression of the disease. Cisternal cerebrospinal fluid (CSF) analysis revealed neutrophilic pleocytosis with increased protein (Table 1). Although less common, we have seen animals with clinical signs of encephalitis for months before referral. { Prognosis } : Sad to say this is generally regarded as an invariably fatal disease with a time course of four or five months at most. One study that says 2.8% of adverse vaccine reactions involve ataxia.

If your rabbit is showing the apparent signs of encephalitis or meningoencephalitis, your veterinarian may be able to diagnose it based on the results of an analysis of cerebrospinal fluid, which can show whether a viral or bacterial agent is present in the fluid. To the authors’ knowledge, information concerning treatment and survival largely has been based on small case series or clinical anecdotes. Since the fast phase of the nystagmus is to the right, we know the vestibular lesion is probably on the left. If a dog of less than 1 or greater than 5 years of age suffers persistent seizures, it should be thoroughly examined and tested for these neurological disorders. Seizures—a manifestation of uncontrolled electrical activity in the cerebral cortex—are the most common canine neurological disorder. The blindness is the result of optic neuritis, and the disease will affect both eyes.

Three months prior to presentation, the dog had been diagnosed with bilateral mild chronic conjunctivitis. Our cases further illustrate that NME is not a breed-restricted disorder and should be considered in the differential diagnosis for dogs with signalment and clinical signs consistent with inflammatory brain disease. The body is “attacking” its own cells and suppression of this is imperative in treatment. Advanced meningitis can cause profound depression, blindness, progressive paralysis, seizures, confusion, agitation, incoordination (ataxia) and/or aggression. This may be an autoimmune disease although viral participation or drug-related causes are possible. This infection is usually nonfatal and occurs after ingesting third-stage larvae of the lungworm in contaminated produce or inadequately cooked snails.7 In the past 2 decades, there have been several reports of an idiopathic form of eosinophilic meningitis that has been shown to affect dogs, cats, and cattle.1–3,6,8–10 In these cases, no infectious etiology has been identified; however, Rottweiler and Golden Retriever dogs appear to be overrepresented, indicating a possible breed predisposition.

Clinically affected dogs may present with acute illness characterized by fever, lethargy, uncontrolled rolling, whole-body tremors, seizures and depression.